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Many cosmetic products are complex colloidal systems and stability is a critical parameter. Shelf-life of such products can reach several years and visual stability analysis can be long and tedious. Turbiscan fits all your needs for stability measurement.

- Emulsion, lotion, cream: decreases significantly the time of stability analysis (up to 200 times).
- Sunscreen: almost impossible to analyse by visual observation, not with the Turbiscan.
- Make-up: detect sedimentation of foundation, nail polish, lipsticks.
- Foam: an easy way to follow the bubble ripening and the drainage.
- Shampoo: stability of pearlescent agents.
- Scale-up: compare stability between lab and process.

 Documentation 

Stabilizing beverage emulsions is a challenging task, since these emulsions are usually highly concentrated, quality of their raw materials may vary, emulsions have to resist to high level of dilution, viscosity should not be too high, etc...
Emulsion destabilization can include size variation which will affect the taste and the long term stability (‘ring’ formation), as well as particle migration (sugar, pulp, proteins). These phenomena may lead the consumer to consider the product as poor quality. Therefore, understanding and enhancing the stability of such products is very important to ensure the best customer perception and the conservation of taste over time.

- Dairy products: quantify and detect characteristic destabilization of milk-based products: droplet size variation, creaming of fat globules, sedimentation of calcium or chocolate particles.
- Flavor emulsions: kinetics of coalescence and flocculation without diluting the sample.
- Soft drinks: detection of ring formation, color change, pulp/sugar/proteins sedimentation.
- Desserts: detect destabilization phenomena of cream, dessert foam, ice cream.
- Raw materials: monitor sharply the efficiency of stabilizers, thickeners, etc.

Documentation

Asphaltenes are causing major problems in the extraction process of crude oil, as they can lead to fouling & clogging in pipes or even in the entire well when they aggregate. Moreover asphaltenes play the role of natural emulsifiers which stabilise water-in-oil emulsions formed during extraction of crude oil. Asphaltenes also have an impact on the refinery efficiency and the fuel oil quality.
To overcome these technical issues, chemical additives are used. It is therefore important to have a technique that can identify the most suitable additive, but also to measure accurately the stability of oil or emulsions.

- Stability of Fuel oil: analyse stability reserve in 15 minutes thanks to the ASTM D-7061
- Stability of Crude oil: analyse aggregation and sedimentation kinetics of asphaltenes
- Efficiency of demulsification: qualify the best additive to demulsify W/O emulsions
- Efficiency of dispersants: measure asphaltenes aggregation kinetics vs dispersant amount
- Quantification of additive: save money by using the proper concentration of additives
- Stability of drilling fluids: detect and quantify destabilisation phenomena

Documentation

The world of drug delivery is getting more and more efficient every day with new forms of products, which are directly targeting the deficient organs. Dispersed systems such as emulsions (simple or multiple) or nanoparticle suspensions (metal oxides, etc.) are now widely used as drug carriers or nutritional solutions in this purpose. These new forms of products allow better targeting and assimilation for the patient, and give rise to new solutions for drug designers.
However, the stability of these inherently unstable colloidal systems makes them complex to formulate and study. Turbiscan enables to detect, qualify and quantify any destabilisation of drug dispersions from product development to quality control.

- Vaccines: kinetics of particles aggregation and sedimentation (proteins, metal oxides….)
- Skin lotion and cream: detection of coalescence and creaming up to 200 times faster than visual test
- Ophthalmic suspension: study of the re-dispersion of active ingredient after storage
- Inhalers (pMDI): study of particles aggregation & sedimentation in pressurized measurement cells

Documentation

TURBISCAN is a widely used method in the formulation world, both in academics and industry.

Feel free to explore our documents (application notes or publications) about all our other application fields:

  • Agrochemicals
  • Chemistry & Raw materials
  • Electronics
  • Paint & Inks
  • Slurries
  • Polymers & Bipolymers
  • And many others...

Documentation

Stability & Shelf life

Stability and shelf-life are key parameters in formulation studies. TURBISCAN is the first patented technology to analyze destabilization mechanisms in concentrated media.
Creaming, sedimentation, agglomeration, aggregation and coalescence are detected at a very early stage without dilution nor stress. Stability kinetics and index are provided for an efficient sample analysis.

Key benefits

  • No Sample preparation
  • 200x faster than conventional tests
  • Quantification of stability

Multiple light scattering technology

The combination of Backscattering and Transmission sensors with a vertical scanner enables to detect physical heterogeneities (size increase or local concentration change) over the whole sample height with a vertical resolution up to 20µm. Thus, nascent destabilization phenomenon can be detected in any sample locations up to 200 times faster than visual tests.

Backscattering or Transmission profiles (i.e signal over sample height) are recorded at different time intervals to report kinetic stability. Stability kinetics are calculated over the whole sample height for a global stability assessment or on specific zone (bottom / middle / top) depending on the stability criteria. Turbiscan Stability Index (TSI) is calculated for easy and accurate stability reporting. Patented sample positioning enables to guaranty an optimal repeatability and reproducibility.

Read more

Data and key features

> Migration analysis

Local variation of light intensity corresponds to phases formation.

  • Phase thickness kinetics
  • Sedimentation rate
  • Creaming rate
  • Particles migration speed
  • Hydrodynamic diameter

> Size Variation analysis

Global variation of light intensity corresponds to size increase.

  • Size kinetics 
  • Mean diameter 
  • Agglomeration rate
  • Coalescence rate
  • Dispersibility ratio 

> Turbiscan Stability Index

Turbiscan Stability Index is a one-click parameter to easily rank the stability of many samples in a kinetic way or in a data table.
The higher the TSI is, the less stable the product is.

Learn more about the TSI

> No mechanical stress

When it comes to shelf-life, and real-life evolution of the end-products, it makes no sense to apply a mechanical stress to a sample. Our measurements are always performed at rest, without any external stress. That way, you can be sure that the results you get are representative of what will happen in real life, only detected way earlier!

Instrument demonstration

Discover our Range

  • > Turbiscan Tower

    THE NEW REFERENCE, 6 TIMES BETTER

    The brand new spearhead of the Turbiscan range to fully characterise the stability of concentrated dispersions (emulsions, suspensions, foams). Discover its new patented mechanical design, for an even better performance. 

    Light source 880 nm
    Detection S-MLS
    Cell Volume 4 or 20 ml
    Quantitative monitoring of dispersion stability *
    Migration velocity & hydrodynamic diameter *
    ISO TR 13097 Compliant *
    Disposable glass cells *
    Turbiscan Stability Index (TSI) computation *
    Automatic samples recognition (bar-code) *
    Mean diameter and volume fraction *
    Temperature control 4 to 80°C
    Multi-samples 6
  • > Turbiscan Lab

    THE REFERENCE STABILITY ANALYZER

    Accelerate and document ageing tests for a fast and deep understanding of destabilization mechanisms (creaming, sedimentation, flocculation, coalescence). Turbiscan LAB can be used in both R&D labs for formulation development and QC labs to control the stability of raw materials and final products. 

    Light source 880 nm
    Detection S-MLS
    Cell Volume 4 or 20 ml
    Quantitative monitoring of dispersion stability *
    Migration velocity & hydrodynamic diameter *
    ISO TR 13097 Compliant *
    Disposable glass cells *
    Turbiscan Stability Index (TSI) computation *
    Automatic samples recognition (bar-code) *
    Mean diameter and volume fraction *
    Temperature control RT to 60°C
  • > Turbiscan AGS

    HIGH-THROUGHPUT STABILITY ANALYZER

    High throughput screening is more and more useful to shorten the formulations time-to-market. Turbiscan AGS integrates the Turbiscan LAB, a robot, a storage station and a smart software for automatic sample handling and treatment. This concept enables an automated management of aging tests from sample storage at different temperatures to shelf-life determination. 

    Light source 880 nm
    Detection S-MLS
    Cell Volume 20 ml
    Quantitative monitoring of dispersion stability *
    Migration velocity & hydrodynamic diameter *
    ISO TR 13097 Compliant *
    Disposable glass cells *
    Turbiscan Stability Index (TSI) computation *
    Automatic samples recognition (bar-code) *
    Mean diameter and volume fraction *
    Temperature control RT to 60°C
    Multi-samples 54
    Storage at 3 different temperatures *
  • > Turbiscan Classic 2

    BASICS OF THE TECHNOLOGY, FOR SHORT-TERM STABILITY STUDIES

    Turbiscan CLASSIC 2 helps to optimize the pre-formulation work by giving a quick insight into the instability phenomena. This updated version of the first Turbiscan is still a success after 20 years.
    Brochure Classic 2
    The OIL SERIES version is ASTM D-7061 compliant, and enables characterization of heavy fuels and crude oils.
    Brochure Oil Series

    Light source 850 nm
    Detection S-MLS
    Cell Volume 7 ml
    Quantitative monitoring of dispersion stability *
    Migration velocity & hydrodynamic diameter *
    ISO TR 13097 Compliant *
    ASTM D-7061 Compliant Oil Series option
    Disposable glass cells No
    Turbiscan Stability Index (TSI) computation No
    Automatic samples recognition (bar-code) No
    Mean diameter and volume fraction No
    Temperature control No
    Multi-samples No